Exosomes for skin

What are exosomes? What do they do for skin?

Exosomes are microscopic biological messengers naturally released by cells. They carry powerful signals that instruct skin cells to repair, regenerate, and function more efficiently. Due to their extremely small size, exosomes can penetrate deeply into the skin, where they activate fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid.

Unlike traditional skincare ingredients that work only on the surface, exosomes communicate directly with skin cells, triggering advanced regeneration processes from within.

There are multiple exosome products on the market. This clinic has selected 3 for skin. 1 is plant derived (iD-EXO), and 2 are derived from the first milk of cows (Purasomes). They can be used across multiple areas.

Plant based exosome. iD-Exo

Why choose plant-based exosomes?

Plant-derived exosomes offer several advantages in aesthetic treatments:

High safety profile with minimal risk of immune reaction
Non-animal derived, eliminating the risk of animal-borne pathogens
Biocompatible and suitable for all skin types
Sustainable and ethically sourced

This makes iD-EXO™ a safe, effective, and future-focused regenerative treatment which is usually paired with Bio-Spicules microneedling.

iD-EXO™ uses plant-based exosomes derived from mandarin extract. Once applied to the skin (typically following microneedling), these exosomes:

Stimulate collagen and elastin production
Increase hyaluronic acid for deep hydration and plumpness
Reduce inflammation and oxidative stress
Support wound healing and tissue repair
Help regulate enzymes linked to skin ageing

This dual action — activating cell signalling pathways while delivering regenerative genetic instructions — makes exosomes one of the most advanced tools in aesthetic skin rejuvenation.

Benefits of iD-EXO™ treatment

Clients may experience:

Improved skin firmness and elasticity
Smoother texture and refined pores
Reduction in fine lines and wrinkles
Enhanced skin hydration and radiance
Faster recovery following aesthetic procedures
Support for acne scarring, pigmentation, and skin laxity

Because iD-EXO™ works with the skin’s natural repair mechanisms, results continue to improve over time.

Treatment experience

iD-EXO™ is typically applied following microneedling (often with Bio-Spicules) to maximise absorption. The treatment is minimally invasive, involves little to no downtime, and does not require injections. Clients are advised to avoid active skincare products for 24–36 hours post-treatment to allow optimal exosome activity.

Who is suitable?

iD-EXO™ is ideal for clients seeking advanced skin rejuvenation without invasive procedures. A full consultation is required, as treatment may not be suitable for individuals with active autoimmune disease, infections, pregnancy, or a history of cancer.

First cow's milk exosomes. Purasomes

2 products are available: Skin Nutri complex (NC150+) for ageing and depleted skin, and Skin Glow Complex (SGC100+) Targeted Brightening & Radiance at Cellular Level.

The treatments are commonly delivered using cosmetic microneedling, allowing optimal penetration of exosomes and active ingredients. Treatments are typically performed as a course of 3–5 sessions, spaced 4–6 weeks apart, with minimal downtime.

Why choose cow's milk exosomes?

The exosomes are derived from bovine colostrum (the first milk of cows_, which is rich in antibodies, growth factors, proteins, vitamins and minerals. It has long been used by humans for health benefits that include boosting immunity and improving gastrointestinal health.

Bovine colostrum is the optimal substitute for human colostrum, while also containing less lactose and more proteins. It has the richest source of growth factors and a high content of antibodies, antioxidants, cytokines, lactoferrin and lactoperoxidase, which all contribute to effective skin (and hair )regeneration.

The colostrum used is harvested from grass-fed cattle on an Italian Organic Certified family farm within the first one to five hours after birth. The process used ensures that calves are never deprived of colostrum, which is key for their growth and development.

It is then delivered and processed in specially equipped transport to the Dermoaroma production site within 24 to 48 hours.

When it arrives, the bovine colostrum is purified so only the most potent biologically active elements are utilised. Using a centrifuge, exosomes and growth factors are isolated, allowing impurities such as fat, dead cells and debris to be discarded.

The exosomes and growth factors then go through a reliable dehydrating process, which allows them to be stored at room temperature without comprising their integrity. The end product is a 5ml vial containing 200mg of 20 billion exosomes and 20 of the most potent growth factors ready for use.

Purasomes® Skin Nutri Complex

Advanced Cellular Re-Architecture for Ageing & Depleted Skin

Purasomes® Nutri Complex (NC150+) is an advanced regenerative skin treatment designed to deeply nourish, repair, and reprogram tired, ageing skin at a cellular level. Developed using patented AMPLEX Plus® Technology by Dermoaroma, it combines high-purity exosomes, potent growth factors, and biomimetic actives to restore skin performance associated with a more youthful state.

How it works

Nutri Complex delivers an exceptionally high concentration of 20 billion purified exosomes and 20 growth factors, derived from organic bovine colostrum, alongside dual-weight hyaluronic acid, amino acids, vitamins, co-enzymes, and PDRN.

When introduced into the skin — typically via microneedling — these bioactive messengers:

Reprogram cellular activity to enhance regeneration
Stimulate fibroblast function for collagen and elastin production
Improve dermal density and skin thickness
Restore hydration and elasticity
Support angiogenesis and tissue repair

Rather than working superficially, Nutri Complex actively re-architects the skin from within, improving both structure and function over time.

Key benefits

Nutri Complex is ideal for mature, dry, stressed, or photo-damaged skin, delivering:

Improved skin thickness and firmness
Enhanced hydration within 2 weeks
Improved elasticity and resilience within 4 weeks
Brighter, healthier skin tone
Long-term strengthening of the skin framework
Visible rejuvenation with cumulative results

Why choose Purasomes® Nutri Complex?

Extremely high exosome and growth factor concentration
Deeply nourishing and restorative
Designed for long-term skin resilience, not just short-term glow
Minimally invasive with minimal downtime
Suitable for clients seeking advanced anti-ageing without injectables

Recommended treatment schedule

3 sessions every 3-4 weeks.

Purasomes® Skin Glow Complex

Purasomes® Skin Glow Complex (SGC100+) is a high-performance brightening and complexion-correcting treatment designed to restore luminosity, reduce pigmentation irregularities, and protect the skin from oxidative stress.

By combining purified exosomes, growth factors, antioxidants, peptides, and plant-derived pomegranate stem cells, Skin Glow Complex works at the source of pigmentation rather than masking it.

How it works

By combining purified exosomes, growth factors, antioxidants, peptides, and plant-derived pomegranate stem cells, Skin Glow Complex works at the source of pigmentation rather than masking it.

How it works

Skin Glow Complex targets the full pigmentation pathway by:

Inhibiting melanin synthesis
Reducing melanosome formation and transfer
Modulating oxidative stress caused by UV exposure
Supporting autophagy-mediated melanosome degradation
Strengthening the skin’s antioxidant defence system

Exosomes act as precision delivery vehicles, ensuring these brightening and protective signals reach deeper skin layers for long-lasting results

Key benefits

Clients may experience:

Brighter, more even skin tone
Reduction in hyperpigmentation and sun damage
Enhanced skin luminosity and vitality
Improved skin clarity and radiance
Strengthened barrier function and antioxidant protection

This makes Skin Glow Complex particularly effective for dull, uneven, pigmented, or environmentally stressed skin.

Why choose Purasomes® Skin Glow Complex?

Treats pigmentation at a cellular and molecular level
Non-invasive and suitable for multiple skin types
Ideal as a course of treatments or alongside microneedling
Supports long-term complexion correction rather than temporary brightening

What sort of results are possible with Purasomes?

Photos supplied by distributor from other clinics

Should I choose this instead of polynucleotides?

Many patients actually choose to combine both! Using Plinest to build the skin’s foundation and Purasomes to supercharge the surface renewal often leads to the most “filtered” and radiant finish.

Purasomes offer a more comprehensive, multi-pathway approach to skin rejuvenation. While Plinest focuses on the power of polynucleotides to hydrate and repair DNA at a structural level, Purasomes harness AMPLEX Plus technology to deliver a staggering 20 billion exosomes and 20 targeted growth factors per vial. This “cellular messenger” system doesn’t just hydrate; it actively resets cellular performance to a more youthful state, effectively communicating with your fibroblasts to ramp up collagen and elastin production. If you are looking for a treatment that goes beyond deep hydration to tackle complex concerns like stubborn pigmentation, chronic inflammation, and significant texture irregularities, Purasomes provide a more intensive, nutrient-rich “reset” for tired or environmentally stressed skin.